Effects and mechanisms of trifolin on attenuating hypertension-induced vascular smooth muscle cell proliferation and collagen deposition in vivo and in vitro
Abstract Trifolin exhibits anti-tumor activities; however, its effect on hypertension remains unknown. This study was performed to investigate trifolin’s potential therapeutic effects and underlying mechanisms of action on angiotensin II (Ang II)-induced hypertension in mice and Ang II stimulated A7...
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| Main Authors: | Aling Shen, Meizhu Wu, Zhi Guo, Farman Ali, Jinkong Wu, Hong Chen, Ying Cheng, Dawei Lian, Jun Peng, Min Yu, Keji Chen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-01022-1 |
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