The Nα-acetyl-L-lysine/Loxl2/H2O2 promotes intestinal tumor growth in Drosophila and cell proliferation in human colorectal cancer

The Nα-acetyl-L-lysine/Loxl2/H2O2 promotes intestinal tumor growth in Drosophila and cell proliferation in human colorectal cancer

Summary: A cancer-associated microbiome is considered a carcinogen capable of affecting tumor initiation and/or progression. However, little is known about the molecular mechanisms of tumor-microbiome interactions. Here, we show that Staphylococcus sciuri promotes Drosophila intestinal tumor growth...

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Main Authors: Lei Geng, Zhen Fan, Rongbing Chen, Kyu-Chan Cho, Yining Liu, Yu Cheng, Jingfeng Yang, Ying Zhang, Xuefei Wei, Liyuan Gong, Yingyu Tang, Zhan Xu, Wuren Huang, Shahzad Toufeeq, Zongzhao Zhai, Lei Pan, Jun Zhang, Bin Li, Brenda T. Beerntsen, Ji-Hoon Lee, Youli Xiao, Younghwa Na, Won-Jae Lee, Erjun Ling
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Cell Reports
Subjects:
CP: Microbiology
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725008976
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