Genetic Interplay Between Attention-Deficit/Hyperactivity Disorder and Pain Suggests Neurodevelopmental Pathways and Comorbidity Risk

Genetic Interplay Between Attention-Deficit/Hyperactivity Disorder and Pain Suggests Neurodevelopmental Pathways and Comorbidity Risk

Background: In this study, we investigated the genetic connections between attention-deficit/hyperactivity disorder (ADHD), migraine (MGN), and multisite chronic pain (MCP). The goal was to identify specific shared biological mechanisms that contribute to the overlap between ADHD and these pain-rela...

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Bibliographic Details
Main Authors: Nicolas P. Ciochetti, Victor F. de Oliveira, Iago Junger-Santos, Cibele E. Bandeira, Maria E. Tavares, Eduardo S. Vitola, Luis A. Rohde, Gustavo Melo de Andrade, Bruna S. da Silva, Eugenio H. Grevet, Claiton H. Dotto Bau, Diego L. Rovaris
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Biological Psychiatry Global Open Science
Subjects:
Attention-deficit/hyperactivity disorder
Genome-wide association study
Migraine
Pain
Pleiotropy
Polygenic risk score
Online Access:http://www.sciencedirect.com/science/article/pii/S2667174325000710
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