Overexpression of Bmp4 induces microphthalmia by disrupting embryonic neural retina

Microphthalmia, mostly an autosomal dominant disorder, is a worldwide severe congenital ocular malformation that causes visual impairment. Our investigation unveiled a total of 30 genes associated with microphthalmia. Employing the CytoHubba and PPI network, we identified Bmp4 as the most pivotal hu...

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Bibliographic Details
Main Authors: Baige Li, Zeyuan Pu, Keren Liao, Yuxin Du, Gao Tan, Scott Nawy, Shiqiang Gao, Yin Shen
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Neurobiology of Disease
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Online Access:http://www.sciencedirect.com/science/article/pii/S0969996124002547
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