An integrative analysis of cell-specific transcriptomics and nuclear proteomics of sleep-deprived mouse cerebral cortex

Abstract Sleep regulation follows a homeostatic pattern. The mammalian cerebral cortex is the repository of homeostatic sleep drive and neurons and astrocytes of the cortex are principal responders of sleep need. The molecular mechanisms by which these two cell types respond to sleep loss are not ye...

Full description

Saved in:
Bibliographic Details
Main Authors: Pawan K. Jha, Utham K. Valekunja, Akhilesh B. Reddy
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-10783-8
Tags: Add Tag
No Tags, Be the first to tag this record!