Venezuelan equine encephalitis virus non-structural protein 3 dictates superinfection exclusion in mammalian cells

Venezuelan equine encephalitis virus non-structural protein 3 dictates superinfection exclusion in mammalian cells

Abstract Superinfection exclusion (SIE) prevents secondary infections of already infected cells. Arthritogenic alphaviruses induce SIE via early proteolytical cleavage of replicase precursor by non-structural protein 2 (nsP2). Here, we explore the SIE mechanism of the encephalitic Venezuelan equine...

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Main Authors: Tessy A. H. Hick, Taja Zotler, Davita Bosveld, Corinne Geertsema, Monique M. van Oers, Gorben P. Pijlman
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Series:npj Viruses
Online Access:https://doi.org/10.1038/s44298-024-00055-z
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https://doi.org/10.1038/s44298-024-00055-z

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