Metabolic characteristics of benign and malignant pulmonary nodules and establishment of invasive lung adenocarcinoma model by high-resolution mass spectrometry

Metabolic characteristics of benign and malignant pulmonary nodules and establishment of invasive lung adenocarcinoma model by high-resolution mass spectrometry

Abstract Background Increasing pulmonary nodule presentations in lung adenocarcinoma patients reveal diagnostic limitations of CT-based invasiveness assessment. The critical unmet need lies in developing non-invasive biomarkers differentiating invasive adenocarcinoma from premalignant lesions and be...

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Main Authors: Junbao Zhang, Zhihan Zhang, Yuying Liu, Yanyi Hou, Ruifang Pang, Yuenan Wang, Ping Xu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Cancer
Subjects:
Lung nodules
Lung adenocarcinoma
Metabolomics
High-resolution mass spectrometry
Noninvasive metabolomic model
Online Access:https://doi.org/10.1186/s12885-025-14253-2
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https://doi.org/10.1186/s12885-025-14253-2

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