Living therapeutics of nonpathogenic bacteria as biosynthesis factory and active carriers for enhancing tumor-targeted therapy

Abstract Anaerobic bacteria-mediated tumor therapy faces multiple challenges, including potential toxic side effects, complex manufacturing processes, and impaired hypoxic targeting. Here, based on the excellent biocompatibility and distinctive metabolic ability of natural anaerobic sulfate-reducing...

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Bibliographic Details
Main Authors: Mengna Dong, Xinhui Yang, Wenqian Zhang, Yuzhi Qiu, Peng Song, Hongfang Liu, Yajiang Yang, Xiangliang Yang, Qin Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61675-4
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