Effects of simvastatin pretreatment on platelet activation and hypercoagulable state in septic mice

Abstract Objective To investigate the effects of simvastatin pretreatment on platelet activation and hypercoagulable state in septic mice. Method 60 Sprague–Dawley (SD) mice were divided into three groups: healthy control (group A), sepsis (group B) and simvastatin intervention (group C). The sepsis...

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Bibliographic Details
Main Authors: Fan Wu, Ke Xu, Wei Xiong
Format: Article
Language:English
Published: BMC 2025-05-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-025-02677-2
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