Structure and function of vimentin in the generation and secretion of extracellular vimentin in response to inflammation

Abstract The canonical functions of vimentin in cell mechanics and migration have been recently expanded by the discovery of new roles for extracellular vimentin (ECV) in immune responses to infection, injury and cancer. In contrast with the predominantly filamentous form of intracellular vimentin,...

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Bibliographic Details
Main Authors: Zhiyao Yuan, Paul A. Janmey, Christopher A. McCulloch
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-025-02194-z
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