Macrophages promote aberrant DNA repair in multiple myeloma via the CXCL5/8-CXCR2 axis

Macrophages promote aberrant DNA repair in multiple myeloma via the CXCL5/8-CXCR2 axis

Multiple myeloma (MM) is closely associated with abnormal DNA repair and genome instability. The bone marrow microenvironment, particularly myeloma associated macrophages (MΦs) is critical to the progression of MM. However, there is limited understanding on the role of MΦs in DNA repair in MM. Here...

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Bibliographic Details
Main Authors: Mengmeng Dong, Donghua He, Jinna Zhang, Haimeng Yan, Haoguang Chen, Enfan Zhang, Yili Feng, Jingsong He, Xi Huang, Guoqiao Chen, Xiuna Sun, Fei Cheng, Huiyao Gu, Huanping Wang, Anyong Xie, Zhen Cai, Cai Lab
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-06-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12135
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https://haematologica.org/article/view/12135

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