Targeted screening and single-cell analysis of genetic variants in melanoma using Mendelian randomization

Targeted screening and single-cell analysis of genetic variants in melanoma using Mendelian randomization

Abstract Background This study utilizes Mendelian randomization to investigate melanoma’s epidemiological patterns and genetic variants for improved disease prevention and control. Methods We combined SNP data from GTEx V8 eQTL and FinnGen databases for Mendelian randomization analysis, and performe...

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Bibliographic Details
Main Authors: Shi Li, Kaijiong Zhang, Guiji Zhang, Min Shi, Xing Yin, Bo Wang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
Mendelian randomization
Melanoma
SNPs
Genetic variants
Single-Cell analysis
Online Access:https://doi.org/10.1007/s12672-025-03225-4
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https://doi.org/10.1007/s12672-025-03225-4

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