Operational challenges and lessons learned from conducting febrile surveillance in a long-term randomized dengue vaccine trial in Latin America and Asia-Pacific

Operational challenges and lessons learned from conducting febrile surveillance in a long-term randomized dengue vaccine trial in Latin America and Asia-Pacific

Background: In trials, dengue vaccine efficacy evaluation relies on participants presenting with febrile illness/clinically suspected dengue contacting the study site for sample collection and clinical assessment within a short timeframe. Here, we present key considerations to maintain high complian...

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Main Authors: Harald Pfaar, Eduardo López-Medina, Ian Escudero, Yanee Hutagalung, Nicholas Roubinis, Seloni Thakrar, Charissa Fay Corazon Borja-Tabora, Vianney Tricou, Suely Tuboi
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Travel Medicine and Infectious Disease
Subjects:
Dengue
Vaccine
Febrile surveillance
Operational aspects
Children
Adolescents
Online Access:http://www.sciencedirect.com/science/article/pii/S1477893925000468
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