Notoginsenoside R2 attenuates hepatic fibrosis via STAT3-dependent hepatic stellate cells senescence induction and inflammatory microenvironment suppression

Background: Hepatic fibrosis (HF) continues to be a significant global health concern, substantially contributing to morbidity and mortality due to the absence of effective therapeutic options. This study examines the pharmacological effectiveness and underlying mechanisms of Notoginsenoside R2 (R2)...

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Bibliographic Details
Main Authors: Kaili Deng, Min Li, Yuanyuan Li, Liangliang Xiang, Yuhua Wang, Hechen Shi, Jiayi Cheng, Sha Huang, Zhiping Lv
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Journal of Ginseng Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845325000685
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