The C-terminal domain of CENP-C displays multiple and critical functions for mammalian centromere formation.

CENP-C is a fundamental component of functional centromeres. The elucidation of its structure-function relationship with centromeric DNA and other kinetochore proteins is critical to the understanding of centromere assembly. CENP-C carries two regions, the central and the C-terminal domains, both of...

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Bibliographic Details
Main Authors: Stefania Trazzi, Giovanni Perini, Roberto Bernardoni, Monica Zoli, Joseph C Reese, Andrea Musacchio, Giuliano Della Valle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0005832&type=printable
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