The Bordetella effector protein BteA induces host cell death by disruption of calcium homeostasis

The Bordetella effector protein BteA induces host cell death by disruption of calcium homeostasis

ABSTRACT Bordetella pertussis is the causative agent of whooping cough in humans, a disease that has recently experienced a resurgence. In contrast, Bordetella bronchiseptica infects the respiratory tract of various mammalian species, causing a range of symptoms from asymptomatic chronic carriage to...

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Main Authors: Martin Zmuda, Eliska Sedlackova, Barbora Pravdova, Monika Cizkova, Marketa Dalecka, Ondrej Cerny, Tania Romero Allsop, Tomas Grousl, Ivana Malcova, Jana Kamanova
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:mBio
Subjects:
Bordetella
type III secretion system (T3SS)
effector protein BteA
calcium homeostasis
host cell death mechanism
Online Access:https://journals.asm.org/doi/10.1128/mbio.01925-24
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https://journals.asm.org/doi/10.1128/mbio.01925-24

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