Nanoengineered-based delivery systems to modulate CD4+ T cell responses in cancer: emerging paradigms in cancer immunotherapy

Nanoengineered-based delivery systems to modulate CD4+ T cell responses in cancer: emerging paradigms in cancer immunotherapy

BackgroundCD4+ T-cells play a pivotal role in cancer immunology, functioning as both tumor-suppressing and tumor-promoting agents depending on their differentiation and cytokine profiles. Targeting CD4+ T-cells with novel drug delivery systems, particularly nanoparticle-based formulations, offers a...

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Bibliographic Details
Main Authors: Nekhat Shahreen, Anukrati Agnihotri, Asfi Rizwan, Faizul Hasan, Mohd Danish Ansari, Zarif Mohamed Sofian, Nur Akmarina B. M. Said, Kenneth K. W. To, Syed Mahmood
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pharmacology
Subjects:
CD4+ T-cells
cancer immunology
nanoformulation
novel drug delivery systems
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1643791/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1643791/full

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