Cell-free regenerative medicine: identifying the best source of mesenchymal stem cells for skin therapy in Systemic Sclerosis

Cell-free regenerative medicine: identifying the best source of mesenchymal stem cells for skin therapy in Systemic Sclerosis

IntroductionSystemic Sclerosis (SSc) is a rare chronic systemic autoimmune disease characterized by fibrosis of the skin and internal organs and vasculopathy. Raynaud’s phenomenon is typically the earliest clinical manifestation accompanied by skin inflammation, finger ulcers, and organ manifestatio...

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Main Authors: Filomena Napolitano, Valentina Giudice, Vittoria D’Esposito, Nella Prevete, Pasqualina Scala, Amato de Paulis, Carmine Selleri, Pietro Formisano, Francesca Wanda Rossi, Nunzia Montuori
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mesenchymal stem cells
secretome
adipose tissue
bone marrow
Wharton’s jelly
umbilical cord
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1518412/full
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https://www.frontiersin.org/articles/10.3389/fcell.2025.1518412/full

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