Time-dose response and mechanistic specificity of berberine in renal fibrosis from a multi-model integration perspective: a systematic review and meta-analysis on animal models

ObjectiveThis research intends to comprehensively evaluate the efficacy of berberine (BBR) and the specificity of its mechanisms of action in different animal models of renal fibrosis through a multi-model integration strategy.MethodsA comprehensive search of animal experimental studies was carried...

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Bibliographic Details
Main Authors: Ruyi Nie, Ziting Yuan, Yizhe Wu, Minqi Pan, Jiandong Lu, Guoliang Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1600408/full
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