Fecal microbiota transplantation alleviates lipopolysaccharide-induced osteoporosis by modulating gut microbiota and long non-coding RNA TUG1 expression

Fecal microbiota transplantation alleviates lipopolysaccharide-induced osteoporosis by modulating gut microbiota and long non-coding RNA TUG1 expression

PurposeTo study whether fecal microbiota transplantation (FMT) can alleviate lipopolysaccharide (LPS)-induced osteoporosis (OP) by regulating the composition and abundance of gut microbiota and the expression level of long non-coding RNA (lncRNA) TUG1.MethodsTwenty C57BL/6 mice were selected. Two mi...

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Main Authors: Pengcheng Ma, Ruoyi Wang, Huizhi Chen, Jiachun Zheng, Weijie Yang, Bo Meng, Yifan Liu, Yao Lu, Jing Zhao, Hongwei Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
fecal microbiota transplantation
osteoporosis
gut microbiota
lncRNA
lipopolysaccharides
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1535666/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1535666/full

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