Hypoxic Neural Stem Cells Enhance Spinal Cord Repair Through HIF‐1a/RAB17‐Driven Extracellular Vesicle Release

Hypoxic Neural Stem Cells Enhance Spinal Cord Repair Through HIF‐1a/RAB17‐Driven Extracellular Vesicle Release

ABSTRACT Spinal cord injury (SCI) is a severe and complex condition that can lead to significant physical impairments and affect the life quality of patients. Neural stem cells (NSCs) transplantation holds as a promising therapeutic approach for SCI. However, the challenging post‐SCI microenvironmen...

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Main Authors: Tian Qin, Yiming Qin, Haicheng Wen, Tianding Wu, Chunyue Duan, Yong Cao, Yi Sun, Hongkang Zhou, Hongbin Lu, Liyuan Jiang, Jianzhong Hu, Chengjun Li
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Journal of Extracellular Vesicles
Subjects:
CAQK/Angiopep2 peptides
extracellular vesicles
hypoxia
neural stem cells
spinal cord injury
Online Access:https://doi.org/10.1002/jev2.70126
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https://doi.org/10.1002/jev2.70126

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