Development of chimeric MrNV virus-like particles capable of binding to SARS-CoV-2-susceptible cells and reducing infection by pseudovirus variants

Development of chimeric MrNV virus-like particles capable of binding to SARS-CoV-2-susceptible cells and reducing infection by pseudovirus variants

Abstract SARS-CoV-2, the cause of COVID-19, primarily targets lung tissue, leading to pneumonia and lung injury. The spike protein of this virus binds to the common receptor on susceptible tissues and cells called the angiotensin-converting enzyme-2 (ACE2) of the angiotensin (ANG) system. In this st...

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Bibliographic Details
Main Authors: Supawich Boonkua, Orawan Thongsum, Purimpuch Soongnart, Rueangtip Chantunmapitak, Somkid Jaranathummakul, Kitima Srisanga, Somluk Asuvapongpatana, Patompon Wongtrakoongate, Wattana Weerachatyanukul, Atthaboon Watthammawut, Monsicha Somrit
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Virus-like particle
Macrobrachium rosenbergii nodavirus (MrNV)
Nanotechnology
Genetic modification
SARS-CoV-2
Recombinant capsid protein
Online Access:https://doi.org/10.1038/s41598-024-83024-z
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https://doi.org/10.1038/s41598-024-83024-z

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