Structure-based virtual screening of Trachyspermum ammi metabolites targeting acetylcholinesterase for Alzheimer's disease treatment.

In recent decades, Alzheimer's disease (AD) has garnered significant attention due to its rapid global prevalence. The cholinergic hypothesis posits that the degradation of acetylcholine by acetylcholinesterase (AChE) contributes to AD development. Despite existing anti-AChE drugs, their advers...

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Bibliographic Details
Main Authors: Mohammed Sakib Musa, Md Tahsinul Islam, Wasif Billah, Md Siam Hossain, Md Shirajuce Shalakin Rahat, Imren Bayil, Yeasmin Akter Munni, Sumon Ganguli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0311401
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