Neoadjuvant atezolizumab plus bevacizumab prior liver transplantation for hepatocellular carcinoma

Neoadjuvant atezolizumab plus bevacizumab prior liver transplantation for hepatocellular carcinoma

Background & Aims: The combination of atezolizumab and bevacizumab offers a novel approach to immunomodulation, showing efficacy as a primary treatment in advanced hepatocellular carcinoma (HCC). Concerns about graft safety and rejection have limited its exploration in the neoadjuvant settin...

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Main Authors: Parissa Tabrizian, Rebecca Marino, Sherrie Bhoori, Marcus Zeitlhoefler, Neil Mehta, Vanessa Banz, Salvatore Gruttadauria, Massimo Iavarone, Chiara Mazzarelli, Nicolò Simonotti, Francis Yao, Vincenzo Mazzaferro, Josep M. Llovet
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:JHEP Reports
Subjects:
hepatocellular carcinoma
liver transplantation
immunotherapy
atezolizumab
bevacizumab
Immune Checkpoint Inhibitors
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555924002507
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