Optimizing phage therapy for Salmonella Pullorum: dosage, timing, and pharmacokinetics define treatment efficacy in SPF chickens

Optimizing phage therapy for Salmonella Pullorum: dosage, timing, and pharmacokinetics define treatment efficacy in SPF chickens

Phage therapy has emerged as a highly effective antibiotic alternative for treating Salmonella infections; however, research into how phage dosage, administration timing, and frequency influence therapeutic efficacy—along with phage pharmacokinetics—remains limited. In this study, we established a S...

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Bibliographic Details
Main Authors: Lulu Li, Mengrui Zhang, Yumei Cai, Zhengjie Liu, Zhaohui Tang, Zhipeng Zhang, Yujia Liu, Caihong Zhao, Xiaoqing Yu, Bent Petersen, Thomas Sicheritz-Pontén, Martha R.J. Clokie, Yuqing Liu
Format: Article
Language:English
Published: Elsevier 2025-11-01
Series:Poultry Science
Subjects:
Salmonella Pullorum
Phage therapy
Pharmacodynamic
Pharmacokinetic
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579125008843
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