An increase in reactive oxygen species underlies neonatal cerebellum repair

The neonatal mouse cerebellum shows remarkable regenerative potential upon injury at birth, wherein a subset of Nestin-expressing progenitors (NEPs) undergoes adaptive reprogramming to replenish granule cell progenitors that die. Here, we investigate how the microenvironment of the injured cerebellu...

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Bibliographic Details
Main Authors: Anna Pakula, Salsabiel El Nagar, N Sumru Bayin, Jens Bager Christensen, Daniel Stephen, Adam James Reid, Richard P Koche, Alexandra L Joyner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-08-01
Series:eLife
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Online Access:https://elifesciences.org/articles/102515
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