Pregestational Stress Representing a Maternal Depression Model and Prenatally Applied Antidepressant Mirtazapine Modulate Hippocampal Excitability in Offspring

Pregestational Stress Representing a Maternal Depression Model and Prenatally Applied Antidepressant Mirtazapine Modulate Hippocampal Excitability in Offspring

Maternal depression negatively affects the neurodevelopment of offspring, but its pharmacological treatment during gestation remains controversial. This study reports the consequences of maternal depression and/or prenatal antidepressant treatment with mirtazapine on offspring early neurodevelopment...

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Bibliographic Details
Main Authors: Lucia Dubiel-Hoppanova, Alzbeta Filipova, Stanislava Bukatova, Katarina Ondacova, Matus Tomko, Bohumila Jurkovicova-Tarabova, Michal Dubovicky, Eliyahu Dremencov, Lubica Lacinova
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Scientia Pharmaceutica
Subjects:
pregestational stress
maternal depression
prenatal antidepressant treatment
hippocampal excitability
Online Access:https://www.mdpi.com/2218-0532/93/2/17
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