Geranylgeranyl Pyrophosphate Promotes Hepatic Lipid Accumulation by Prenylation of Perilipin4Summary

Geranylgeranyl Pyrophosphate Promotes Hepatic Lipid Accumulation by Prenylation of Perilipin4Summary

Background & Aims: Metabolically unhealthy obesity (MUO) is characterized by hepatic steatosis and type 2 diabetes (T2D), distinct from metabolically healthy obesity (MHO). This study aimed to identify the key regulator responsible for MUO. Methods: Metabolomics analysis was conducted to com...

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Main Authors: Yue Zhao, Hong-Yu Nie, Shan Jiang, Meng-Fei Zhao, Peng Sun, Jing-Zi Zhang, Xiao-Chen Wang, Yi-Ping Tang, Ming-jie Zou, Xian-Wen Yuan, Xi-Tai Sun, Xiao-Dong Shan, Jian He, Jiang-Huai Liu, Yan Bi, Lei Fang, Xiao Han, Chao-Jun Li
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
DGBP
Geranylgeranyl Pyrophosphate (GGPP)
Metabolically Healthy Obesity
Metabolically Unhealthy Obesity
Perilipin4
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X25000876
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http://www.sciencedirect.com/science/article/pii/S2352345X25000876

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