Dual effects of GABAAR agonist anesthetics in neurodevelopment and vulnerable brains: From neurotoxic to therapeutic effects

Dual effects of GABAAR agonist anesthetics in neurodevelopment and vulnerable brains: From neurotoxic to therapeutic effects

Debates regarding the specific effects of general anesthesia on developing brains have persisted for over 30 years. A consensus has been reached that prolonged, repeated, high-dose exposure to anesthetics is associated with a higher incidence of deficits in behavior and executive function, while sin...

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Bibliographic Details
Main Authors: Dihan Lu, Wen Zhang, Keyu Chen, Xia Feng
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2026-01-01
Series:Neural Regeneration Research
Subjects:
brain
central nervous system
cognition
gamma-aminobutyric acid type a receptor agonist
general anesthetics
neurogenesis
neurological disorders
neuroprotection
neurotoxicity
signal pathways
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-24-00828
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https://journals.lww.com/10.4103/NRR.NRR-D-24-00828

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