Recombinant PASylated nanobody probes with improved blood circulation and tumor targeting

Nanobodies have been extensively demonstrated in biomedical imaging and therapy. However, nanobody probes often suffer from rapid renal clearance due to its small size. Herein, we reported a recombinant nanobody with a 200 amino-acid polypeptide chain consisting of Pro, Ala, and Ser (PAS) at the C-t...

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Bibliographic Details
Main Authors: Yicheng Yang, Lingyue Jin, You Zhang, Siyu Zhou, Weijun Wei, Gang Huang, Changfeng Wu
Format: Article
Language:English
Published: World Scientific Publishing 2025-05-01
Series:Journal of Innovative Optical Health Sciences
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Online Access:https://www.worldscientific.com/doi/10.1142/S1793545825410019
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