A novel one-pot microwave assisted green synthesis of pyridinyl-1,3,5-triazine-2,4-diamine hybrids as potent antimicrobial agents

A novel one-pot microwave assisted green synthesis of pyridinyl-1,3,5-triazine-2,4-diamine hybrids as potent antimicrobial agents

Abstract A novel, green, and efficient microwave-assisted synthesis of pyridinyl-1,3,5-triazine-2,4-diamine hybrids was developed using a one-step, multi-component reaction involving 2-aminopyridine, cyanamide, and aromatic aldehydes/ketones or cyclic ketones under neat reaction conditions. This met...

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Main Authors: Omniya Sayed Zaky, Mohamed Hisham, Mohamed Abd-Elmonem, Ramadan Yahia, Laila Abdulmohsen Jaragh-Alhadad, Ramadan Ahmed Mekheimer, Gamal El-Din A. Abuo-Rahma, Moustafa Sherief Moustafa, Manal Makboul Ebied, Kamal Usef Sadek
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Chemistry
Subjects:
Pyridinyl-1,3,5-triazine
Microwave synthesis
Antimicrobial activity
SAR
Urease inhibition
ADMET
Online Access:https://doi.org/10.1186/s13065-025-01481-7
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https://doi.org/10.1186/s13065-025-01481-7

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