Exploring the Epigenetic Landscape of Spermatozoa: Impact of Oxidative Stress and Antioxidant Supplementation on DNA Methylation and Hydroxymethylation

Reproductive success is dependent on gamete integrity, and oxidative stress alters male nuclei, meaning that no DNA repair is possible due to chromatin compaction. The composition of sperm makes it highly sensitive to reactive oxygen species (ROS) but, at the same time, ROS are needed for sperm phys...

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Bibliographic Details
Main Authors: Elisa Hug, Yoan Renaud, Rachel Guiton, Mehdi Ben Sassi, Charles Marcaillou, Aron Moazamian, Parviz Gharagozloo, Joël R. Drevet, Fabrice Saez
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Antioxidants
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Online Access:https://www.mdpi.com/2076-3921/13/12/1520
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