Impact of glycolysis enzymes and metabolites in regulating DNA damage repair in tumorigenesis and therapy
Abstract Initially, it was believed that glycolysis and DNA damage repair (DDR) were two distinct biological processes that independently regulate tumor progression. The former metabolic reprogramming rapidly generates energy and generous intermediate metabolites, supporting the synthetic metabolism...
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Main Authors: | Fengyao Sun, Wen Li, Ruihang Du, Mingchan Liu, Yi Cheng, Jianxing Ma, Siyuan Yan |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12964-025-02047-9 |
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