Combined treatment using bismuth sulfide nanoparticles loaded with NANOG decoy oligodeoxynucleotides under X-ray radiation for breast cancer cells

Combined treatment using bismuth sulfide nanoparticles loaded with NANOG decoy oligodeoxynucleotides under X-ray radiation for breast cancer cells

Abstract Our goal in this study was to develop bismuth sulfide nanoparticles (NPs) that were functionalized with chitosan and incorporated with decoy oligodeoxynucleotides (ODNs) specifically targeting the NANOG transcription factor (designated as Bi@Chi-DEC NPs) in triple-negative breast cancer cel...

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Bibliographic Details
Main Authors: Sara Heidari, Mahmoud Gharbavi, Roghayeh Ghorbani, Hamed Rezaeejam, Behrooz Johari
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Breast cancer
Bismuth nanoparticle
Combinational therapy
Decoy oligodeoxynucleotides (ODNs)
NANOG transcription factor
Radiotherapy
Online Access:https://doi.org/10.1038/s41598-025-05074-1
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https://doi.org/10.1038/s41598-025-05074-1

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