Dissecting the Impact of Maternal Androgen Exposure on Developmental Programming through Targeting the Androgen Receptor

Dissecting the Impact of Maternal Androgen Exposure on Developmental Programming through Targeting the Androgen Receptor

Abstract Women with polycystic ovary syndrome (PCOS) exhibit sustained elevation in circulating androgens during pregnancy, an independent risk factor linked to pregnancy complications and adverse outcomes in offspring. Yet, further studies are required to understand the effects of elevated androgen...

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Main Authors: Haojiang Lu, Hong Jiang, Congru Li, Emilie Derisoud, Allan Zhao, Gustaw Eriksson, Eva Lindgren, Han‐Pin Pui, Sanjiv Risal, Yu Pei, Theresa Maxian, Claes Ohlsson, Anna Benrick, Sandra Haider, Elisabet Stener‐Victorin, Qiaolin Deng
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:Advanced Science
Subjects:
developmental programming
human trophoblast organoids
placental development
polycystic ovary syndrome
Online Access:https://doi.org/10.1002/advs.202309429
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https://doi.org/10.1002/advs.202309429

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