Genetically distinct within-host subpopulations of hepatitis C virus persist after Direct-Acting Antiviral treatment failure.
Analysis of viral genetic data has previously revealed distinct within-host population structures in both untreated and interferon-treated chronic hepatitis C virus (HCV) infections. While multiple subpopulations persisted during the infection, each subpopulation was observed only intermittently. Ho...
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| Main Authors: | Lele Zhao, Matthew Hall, Prahalad Giridhar, Mahan Ghafari, Steven Kemp, Haiting Chai, Paul Klenerman, Eleanor Barnes, M Azim Ansari, Katrina Lythgoe |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-04-01
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| Series: | PLoS Pathogens |
| Online Access: | https://doi.org/10.1371/journal.ppat.1012959 |
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