Altered trabecular bone structure and delayed cartilage degeneration in the knees of collagen VI null mice.

Mutation or loss of collagen VI has been linked to a variety of musculoskeletal abnormalities, particularly muscular dystrophies, tissue ossification and/or fibrosis, and hip osteoarthritis. However, the role of collagen VI in bone and cartilage structure and function in the knee is unknown. In this...

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Bibliographic Details
Main Authors: Susan E Christensen, Jeffrey M Coles, Nicole A Zelenski, Bridgette D Furman, Holly A Leddy, Stefan Zauscher, Paolo Bonaldo, Farshid Guilak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0033397&type=printable
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