Luteolin-Rich Extract from <i>Harrisonia perforata</i> (Blanco) Merr. Root Alleviates SARS-CoV-2 Spike Protein-Stimulated Lung Inflammation via Inhibition of MAPK/NLRP3 Inflammasome Signaling Pathways

Luteolin-Rich Extract from <i>Harrisonia perforata</i> (Blanco) Merr. Root Alleviates SARS-CoV-2 Spike Protein-Stimulated Lung Inflammation via Inhibition of MAPK/NLRP3 Inflammasome Signaling Pathways

The COVID-19-related long-standing effect or Post-Acute Sequelae of COVID-19 (PASC) is often associated with NLRP3 inflammasome activation in pulmonary inflammation elicited by SARS-CoV-2 spike proteins. Spike proteins engage toll-like receptors (TLRs) in respiratory epithelial cells, leading to exc...

Full description

Saved in:
Bibliographic Details
Main Authors: Warathit Semmarath, Punnida Arjsri, Kamonwan Srisawad, Sonthaya Umsumarng, Pornngarm Dejkriengkraikul
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Life
Subjects:
<i>Harrisonia perforata</i>
luteolin
spike protein
Wuhan-origin: Omicron variant
NLRP3 inflammasome
MAPK pathway
Online Access:https://www.mdpi.com/2075-1729/15/7/1077
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2075-1729/15/7/1077

Similar Items