Single-cell analysis reveals antibiotic affects conjugative transfer by modulating bacterial growth rather than conjugation efficiency

Single-cell analysis reveals antibiotic affects conjugative transfer by modulating bacterial growth rather than conjugation efficiency

Antibiotic resistance genes (ARGs) pose a significant threat to human health and the environment. Quantifying the efficiency of horizontal gene transfer (HGT) is challenging due to diverse biological and environmental influences. Single-cell level approaches are well-suited for investigating conjuga...

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Bibliographic Details
Main Authors: Li Liu, Qiang-hong Zhang, Meng-zi Li, Rui-tong Li, Zhiming He, Arnaud Dechesne, Barth F. Smets, Guo-ping. Sheng
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Environment International
Subjects:
Single-cell
Antibiotic resistance genes
Microfluidics
Individual-based modelling
Conjugation efficiency
Fluorescence-based imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412025001369
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