Enhanced Anticancer Activity of 7MeERT over Ertredin: A Comparative Study on Cancer Cell Proliferation and NDUFA12 Binding

Enhanced Anticancer Activity of 7MeERT over Ertredin: A Comparative Study on Cancer Cell Proliferation and NDUFA12 Binding

We have previously identified Ertredin (3-(2-amino-5-bromophenyl) quinoxalin-2(1H)-one) as a compound that suppresses 3D spheroid formation and tumorigenesis in NIH3T3 cells induced by <i>Epidermal Growth Factor Receptor</i> variant III (<i>EGFRvIII</i>) transduction. One of...

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Bibliographic Details
Main Authors: Sonoko Atsumi, Chisato Nosaka, Takefumi Onodera, Hayamitsu Adachi, Takumi Watanabe, Manabu Kawada, Masabumi Shibuya, Se In Park, Ho Jeong Kwon
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Biomolecules
Subjects:
antiproliferative activity
Ertredin
glioblastoma
NDUFA12
oxidative phosphorylation
tumorigenesis
Online Access:https://www.mdpi.com/2218-273X/14/9/1197
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