PerturbNet predicts single-cell responses to unseen chemical and genetic perturbations

Abstract Chemical and genetic perturbations, such as those induced by small molecules and CRISPR, effect complex changes in the molecular states of cells. Despite advances in high-throughput single-cell perturbation screening technology, the space of possible perturbations is far too large to measur...

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Bibliographic Details
Main Authors: Hengshi Yu, Weizhou Qian, Yuxuan Song, Joshua D Welch
Format: Article
Language:English
Published: Springer Nature 2025-07-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/s44320-025-00131-3
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