Magnetic Molecularly Imprinted Polymers with Hydrophilic Shells for the Selective Enrichment and Detection of Rosmarinic Acid in Aqueous Extraction
Rosmarinic acid (RA) is a natural active compound widely found in many plants belonging to the family of <i>Lamiaceae</i>, <i>Boraginaceae</i>, and so on, which has various important bioactivities, including being anti-oxidative, anti-inflammatory, antiviral, etc. Herein, nov...
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2024-12-01
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| author | Yanhui Wang Linlin Yan Guangyao Zheng |
| author_facet | Yanhui Wang Linlin Yan Guangyao Zheng |
| author_sort | Yanhui Wang |
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| description | Rosmarinic acid (RA) is a natural active compound widely found in many plants belonging to the family of <i>Lamiaceae</i>, <i>Boraginaceae</i>, and so on, which has various important bioactivities, including being anti-oxidative, anti-inflammatory, antiviral, etc. Herein, novel hydrophilic magnetic molecularly imprinted polymers (HMMIPs) with a regular core-shell structure were successfully developed using RA as a template molecule, acrylamide (AM) as a functional monomer, N-N ’methylenebisacrylamide (MBA) as a cross-linking agent, and water as the porogen. After a series of characterization and adsorption performance analyses, it was found that HMMIPs are hydrophilic with an adsorption capacity of 8.012 ± 0.54 mg/g, an imprinting factor of 3.64, and a selectivity coefficient of 2.63~2.91. Furthermore, the HMMIPs can be rapidly separated from other components under the influence of external magnetic fields. The HMMIPs were employed for the determination of RA present in the <i>Perilla frutescens</i> and <i>Rosmarinus officinalis</i> aqueous extract with recoveries of 88.2~107.3%. These results indicated that HMMIPs of RA have the benefits of straightforward operation, rapid adsorption, and high selectivity, rendering it an appropriate way for the expedient and selective isolation of RA in an intricate matrix. |
| format | Article |
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| institution | Kabale University |
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| language | English |
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| spelling | doaj-art-55cec6161d0948ef807a46a7a639c2f02025-01-10T13:19:37ZengMDPI AGPlants2223-77472024-12-011415610.3390/plants14010056Magnetic Molecularly Imprinted Polymers with Hydrophilic Shells for the Selective Enrichment and Detection of Rosmarinic Acid in Aqueous ExtractionYanhui Wang0Linlin Yan1Guangyao Zheng2Key Laboratory of Biomass Energy and Material, Jiangsu Province, Key Laboratory of Chemical Engineering of Forest Products, National Forestry and Grassland Administration, National Engineering Research Center of Low-Carbon Processing and Utilization of Forest Biomass, Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Institute of Chemical Industry of Forest Products, CAF, Nanjing 210042, ChinaKey Laboratory of Biomass Energy and Material, Jiangsu Province, Key Laboratory of Chemical Engineering of Forest Products, National Forestry and Grassland Administration, National Engineering Research Center of Low-Carbon Processing and Utilization of Forest Biomass, Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Institute of Chemical Industry of Forest Products, CAF, Nanjing 210042, ChinaKey Laboratory of Biomass Energy and Material, Jiangsu Province, Key Laboratory of Chemical Engineering of Forest Products, National Forestry and Grassland Administration, National Engineering Research Center of Low-Carbon Processing and Utilization of Forest Biomass, Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Institute of Chemical Industry of Forest Products, CAF, Nanjing 210042, ChinaRosmarinic acid (RA) is a natural active compound widely found in many plants belonging to the family of <i>Lamiaceae</i>, <i>Boraginaceae</i>, and so on, which has various important bioactivities, including being anti-oxidative, anti-inflammatory, antiviral, etc. Herein, novel hydrophilic magnetic molecularly imprinted polymers (HMMIPs) with a regular core-shell structure were successfully developed using RA as a template molecule, acrylamide (AM) as a functional monomer, N-N ’methylenebisacrylamide (MBA) as a cross-linking agent, and water as the porogen. After a series of characterization and adsorption performance analyses, it was found that HMMIPs are hydrophilic with an adsorption capacity of 8.012 ± 0.54 mg/g, an imprinting factor of 3.64, and a selectivity coefficient of 2.63~2.91. Furthermore, the HMMIPs can be rapidly separated from other components under the influence of external magnetic fields. The HMMIPs were employed for the determination of RA present in the <i>Perilla frutescens</i> and <i>Rosmarinus officinalis</i> aqueous extract with recoveries of 88.2~107.3%. These results indicated that HMMIPs of RA have the benefits of straightforward operation, rapid adsorption, and high selectivity, rendering it an appropriate way for the expedient and selective isolation of RA in an intricate matrix.https://www.mdpi.com/2223-7747/14/1/56hydrophilic magnetic molecular imprinted polymerrosmarinic acidaqueous extraction |
| spellingShingle | Yanhui Wang Linlin Yan Guangyao Zheng Magnetic Molecularly Imprinted Polymers with Hydrophilic Shells for the Selective Enrichment and Detection of Rosmarinic Acid in Aqueous Extraction Plants hydrophilic magnetic molecular imprinted polymer rosmarinic acid aqueous extraction |
| title | Magnetic Molecularly Imprinted Polymers with Hydrophilic Shells for the Selective Enrichment and Detection of Rosmarinic Acid in Aqueous Extraction |
| title_full | Magnetic Molecularly Imprinted Polymers with Hydrophilic Shells for the Selective Enrichment and Detection of Rosmarinic Acid in Aqueous Extraction |
| title_fullStr | Magnetic Molecularly Imprinted Polymers with Hydrophilic Shells for the Selective Enrichment and Detection of Rosmarinic Acid in Aqueous Extraction |
| title_full_unstemmed | Magnetic Molecularly Imprinted Polymers with Hydrophilic Shells for the Selective Enrichment and Detection of Rosmarinic Acid in Aqueous Extraction |
| title_short | Magnetic Molecularly Imprinted Polymers with Hydrophilic Shells for the Selective Enrichment and Detection of Rosmarinic Acid in Aqueous Extraction |
| title_sort | magnetic molecularly imprinted polymers with hydrophilic shells for the selective enrichment and detection of rosmarinic acid in aqueous extraction |
| topic | hydrophilic magnetic molecular imprinted polymer rosmarinic acid aqueous extraction |
| url | https://www.mdpi.com/2223-7747/14/1/56 |
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