Phytochemical, In Silico, In Vitro, and In Vivo Research on Piptadeniastrum africanum (Fabaceae) Unveiling Anti‐Stereotypic, Anxiolytic, and Analgesic Effects in a Sodium Valproate‐Induced Autistic Disorders Model

Phytochemical, In Silico, In Vitro, and In Vivo Research on Piptadeniastrum africanum (Fabaceae) Unveiling Anti‐Stereotypic, Anxiolytic, and Analgesic Effects in a Sodium Valproate‐Induced Autistic Disorders Model

ABSTRACT Objective Individuals with autistic spectrum disorders (ASD) primarily exhibit deficits in communication and social interaction, along with repetitive behaviors and restricted interests. This disorder is often associated with anxiety, nociceptive disorders, and pain. While medical treatment...

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Main Authors: Ambani Omgba Jeanne Julie, Ngouateu Omer Bébé, Mengue Ngadena Yolande Sandrine, Owona Pascal Emmanuel, Kandeda Kavaye Antoine, Ambamba Akamba Bruno Dupon, Nongni Piebeng Quentin Cicilien, Ngang Nguema Franck Emmanuel, Ngondi Judith Laure, Bilanda Danielle Claude, Dzeufiet Djomeni Paul Désiré
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Brain and Behavior
Subjects:
analgesic
anxiolytic
autistic disorders
Piptadeniastrum africanum
sodium valproate
Online Access:https://doi.org/10.1002/brb3.70408
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https://doi.org/10.1002/brb3.70408

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