Lactate Facilitates Pancreatic Repair Following Acute Pancreatitis by Promoting Reparative Macrophage PolarizationSummary

Lactate Facilitates Pancreatic Repair Following Acute Pancreatitis by Promoting Reparative Macrophage PolarizationSummary

Background & Aims: During acute pancreatitis (AP), glycolysis is enhanced. The upregulation of glycolysis increases the level of metabolite lactate. Lactate has been shown to facilitate tissue repair across various pathologic conditions. However, its role in the recovery following AP remains...

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Main Authors: Jing Jiang, Ruiyan Wang, Pengli Song, Qi Peng, Xuerui Jin, Bin Li, Jianbo Ni, Jie Shen, Jingpiao Bao, Zengkai Wu, Xiaolu Ge, Xingpeng Wang, Guoyong Hu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Lactate
Lactylation
Macrophage
Pancreatic Repair
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X25000761
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http://www.sciencedirect.com/science/article/pii/S2352345X25000761

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