Role of the Inflammasome, IL-1β, and IL-18 in Bacterial Infections

The inflammasome is an important innate immune pathway that regulates at least two host responses protective against infections: (1) secretion of the proinflammatory cytokines IL-1β and IL-18 and (2) induction of pyroptosis, a form of cell death. Inflammasomes, of which different types have been ide...

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Bibliographic Details
Main Authors: Manoranjan Sahoo, Ivonne Ceballos-Olvera, Laura del Barrio, Fabio Re
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2011/212680
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