Protocatechualdehyde induced tumor suppressive autophagy through AMPK/ULK1 signaling pathway in gastric cancer

Protocatechualdehyde induced tumor suppressive autophagy through AMPK/ULK1 signaling pathway in gastric cancer

BackgroundGastric cancer (GC) is one of the primary causes of cancer-related fatalities, which requires novel treatment including traditional Chinese medicine (TCM) to prolong survival. Protocatechualdehyde (PCA), a monomer from Chinese herbs, exhibits an anti-cancer effect by inhibiting proliferati...

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Main Authors: Mingming Ren, Fangqi Ma, Mengmeng Qin, Xiaoyu Sun, Yi Wang, Xiaohong Zhu, Yan Xu, Nida Cao, Ruohan Zhao, Yunchao Zhang, Jiangchuan Zhu, Yongfu Pan, Aiguang Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
gastric cancer
protocatechualdehyde
autophagy
AMPK
ULK1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1563006/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1563006/full

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