Structure‐based computational design of antibody mimetics: challenges and perspectives

Structure‐based computational design of antibody mimetics: challenges and perspectives

The design of antibody mimetics holds great promise for revolutionizing therapeutic interventions by offering alternatives to conventional antibody therapies. Structure‐based computational approaches have emerged as indispensable tools in the rational design of those molecules, enabling the precise...

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Bibliographic Details
Main Authors: Elton J. F. Chaves, Danilo F. Coêlho, Carlos H. B. Cruz, Emerson G. Moreira, Júlio C. M. Simões, Manassés J. Nascimento‐Filho, Roberto D. Lins
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:FEBS Open Bio
Subjects:
de novo design
deep learning
machine learning
protein engineering
protein structure
Online Access:https://doi.org/10.1002/2211-5463.13855
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https://doi.org/10.1002/2211-5463.13855

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