Mediating role of systemic immune-inflammation index between heavy metal exposure and hepatic steatosis/hepatic fibrosis: evidence from NHANES 2005–2020

Mediating role of systemic immune-inflammation index between heavy metal exposure and hepatic steatosis/hepatic fibrosis: evidence from NHANES 2005–2020

BackgroundModerate heavy metals can lead to the occurrence of liver injury, but the specific mechanism remains unclear.MethodsThis study, based on data from the National Health and Nutrition Examination Survey (NHANES), analyzed associations between 10 heavy metals and hepatic injury in 5,613 adults...

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Bibliographic Details
Main Authors: Ningning Wang, Xuying Li, Rui He, Xiujuan Zheng, Mingqi Li, Shijing Nian, Kewei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Nutrition
Subjects:
hepatic steatosis
hepatic fibrosis
systemic immune verification index
heavy metal
mediating effect
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1566345/full
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https://www.frontiersin.org/articles/10.3389/fnut.2025.1566345/full

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