Unveiling the significance of AKAP79/150 in the nervous system disorders: An emerging opportunity for future therapies?

Unveiling the significance of AKAP79/150 in the nervous system disorders: An emerging opportunity for future therapies?

A-kinase anchoring protein 79/150 (AKAP79/150) is a crucial scaffolding protein that positions various proteins at specific synaptic sites to modulate excitatory synaptic intensity. As our understanding of AKAP79/150's biology deepens, along with its significant role in the pathophysiology of v...

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Bibliographic Details
Main Authors: Chen-Chao Chu, Ya-Hui Hu, Gui-Zhou Li, Jiang Chen, Ning-Ning Zhang, Yi-Xue Gu, Shi-Yu Wu, Hai-Feng Zhang, Yang-Yang Xu, Hong-Li Guo, Xin Tian, Feng Chen
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Neurobiology of Disease
Subjects:
AKAP79/150
Structure and biological functions
Inflammatory pain
Epilepsy
Depression
Potential therapeutics
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996125000282
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