Ginsenoside Rb1 ameliorates post-doxorubicin treatment myocardial hypertrophy via CaN/NFATc4/GATA4

Ginsenoside Rb1 ameliorates post-doxorubicin treatment myocardial hypertrophy via CaN/NFATc4/GATA4

Background: Myocardial hypertrophy is a crucial pathological change that occurs during post-anthracycline treatment cardiomyopathy. The effects of ginsenoside Rb1 (Rb1) on anthracycline-induced hypertrophy remain unclear. This study aimed to explore the antihypertrophic effect of Rb1 on post-doxorub...

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Main Authors: Jin-Jin Chang, Li-Xia Xu, Wen-Jing Yi, Huan-Huan Zhang, Jun-Wei Zhang, Bin Zheng, Ping-Ying Fu, Rui-Lan He, Rui-Xing Wang, Jian-Feng Jiang, Long-Xin Gui, Min-Xia Wu, Jun-Jin Lin, Zhi-Hong Huang, Jia-Lin Song, Mo-Jun Lin, Hai-Xia Jiao, Zhi-Juan Wu
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Journal of Ginseng Research
Subjects:
Ginsenoside Rb1
Post-doxorubicin treatment
Myocardial hypertrophy
Fibrosis
CaN/NFATc4/GATA4
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845325000958
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